Memorial Hospital Research Laboratories

The Ola Landgren Lab

Research

Ola Landgren
Ola Landgren, MD, PhD
Principal Investigator

The Myeloma Genomic Laboratory

Our laboratory integrates clinical, computational, and molecular biology expertise to determine the genomic drivers underlying initiation and progression of lymphoproliferative disorders. We aim to inform new strategies for early detection, prevention, and treatment of these diseases. Our laboratory is uniquely positioned within the Myeloma Service at the Department of Medicine at MSKCC, a world-leader in early drug development, providing state-of-the-art care for multiple myeloma patients across the United States and internationally. This ensures access to patient samples and clinical data derived from the use of cutting-edge therapies (e.g., CAR-T and bi-specific antibodies). Together with a strong network of collaborators, we are currently interrogating large datasets of whole genome, exome, and RNA sequencing to determine the impact of mutational signatures, structural variants, and rare drivers on multiple myeloma pathogenesis and clinical outcome.

Research Projects

The Ola Landgren Lab

Publications

Even H Rustad, Venkata Yellapantula, Daniel Leongamornlert, Niccolò Bolli, Ledergor Guy, Ferran Nadeu, Nicos Angelopoulos, Kevin J. Dawson, Thomas J. Mitchell, Rob Osborne, Bachisio Ziccheddu, Cristiana Cariniti, Vittorio Montefusco, Paolo Corradini, Kenneth C. Anderson, Philippe Moreau, Elli Papaemmanuil, Ludmil Alexandrov, Xose S. Puente,Elias Campo, Reiner Siebert, Herve Avet-Loiseau, Ola Landgren, Nikhil Munshi, Peter J. Campbelland Francesco Maura. Timing the initiation of multiple myeloma. Available as preprint on Sneak Peek 2019. doi: http://dx.doi.org/10.2139/ssrn.3409453

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People

Ola Landgren

Ola Landgren, MD, PhD

Principal Investigator

  • Dr. Landgren’s and Dr. Maura’s research agenda focuses on the role of genomic alterations in the pathogenesis and progression of multiple myeloma and other lymphoproliferative disorders.
  • MD, Karolinska Institutet
212-639-5153
Office Phone

Members

Ola Landgren
Ola Landgren

Co-Principal Investigator

Francesco Maura
Francesco Maura

Co-Principal Investigator

Benjamin Diamond
Benjamin Diamond

Clinical fellow

Malin Hultcrantz
Malin Hultcrantz

Assistant Attending

Kylee Maclachlan
Kylee Maclachlan

Postdoctoral fellow

Even H. Rustad
Even H. Rustad

Postdoctoral fellow

Teja Venkata
Teja Venkata

Engineer

Lab Affilations

Achievements

  • Multiple Myeloma Research Foundation Immuno-Network Grant -- 2018
  • American Society of Clinical Investigation (ASCI) -- 2012

Open Positions

Ola Landgren Lab: Postdoctoral Researcher

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