The Alexandros Pertsinidis Lab: Projects

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Transcription Initiation of Eukaryotic mRNA Coding Genes
We are interested in the structure and dynamics of the human RNA Polymerase II transcription apparatus.
Mechanisms of Repair and Lesion By-pass DNA Polymerases
We are investigating the mechanisms of nucleotide excision and translesion synthesis of DNA Polymerase enzymes.
Molecular Architecture of Chemical Synapses in the Mammalian Brain
We are reconstructing the molecular-scale organization of the neurotransmitter release machinery.