Dirk Remus: Publications

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Scherr MJ, Wahab SA, Remus D, Duderstadt KE. Mobile origin-licensing factors confer resistance to conflicts with RNA polymerase. Cell Rep. 2022 Mar 22;38(12):110531. doi: 10.1016/j.celrep.2022.110531.

Castaneda JC, Schrecker M, Remus D*, Hite RK*. Mechanisms of loading and release of the 9-1-1 checkpoint clamp. Nat Struct Mol Biol. 2022 Mar 21. doi: 10.1038/s41594-022-00741-7. Epub ahead of print. *corresponding author

Philip J, Örd M, Silva A, Singh S, Diffley JF, Remus D, Loog M, Ikui AE. Cdc6 is sequentially regulated by PP2A-Cdc55, Cdc14, and Sic1 for origin licensing in S. cerevisiae. Elife. 2022 Feb 10;11:e74437. doi: 10.7554/eLife.74437. PMCID: PMC8830886.

Kumar, C., Batra, S., Griffith, J.D., and Remus, D. (2021). The interplay of RNA:DNA hybrid structure and G-quadruplexes determines the outcome of R-loop-replisome collisions. eLife 2021 Sep 8;10:e72286.

Abd Wahab S and Remus D. Antagonistic control of DDK binding to licensed replication origins by Mcm2 and Rad53. eLife 2020; Jul 23;9:e58571. doi: 10.7554/eLife.58571.

Meng X, Wei L, Devbhandari S, Zhang T, Xiang J, Remus D, Zhao X. The Pol e catalytic core plays a structural role in replisome assembly and relies on a unique domain for efficient strand synthesis. Nature Communications 2020; 11(1):2437.

Devbhandari S and Remus D. Rad53 limits CMG helicase uncoupling from DNA synthesis at replication forks. Nature Structural and Molecular Biology 2020; 27(5):461-471.

Gan H, Yu C, Devbhandari S, Sharma S, Han J, Chabes A, Remus D, Zhang Z. Checkpoint kinase Rad53 couples leading- and lagging-strand DNA synthesis under replication stress. Molecular Cell 2017; 68: 446-455.

Frigola J, He J, Kinkelin K, Pye VE, Renault L, Douglas ME, Remus D, Cherepanov P, Costa A, Diffley JFX. Cdt1 stabilizes an open MCM ring for helicase loading. Nature Communications 2017; 8: 15720

Devbhandari S, Jiang J, Kumar C, Whitehouse I, and Remus D. Chromatin constrains the initiation and elongation of DNA replication. Molecular Cell 2017; 65: 131-141

Kumar C & Remus D. Eukaryotic replication origins: Strength in flexibility. Nucleus 7, 292-300 (2016).

Remus D. The role of Mcm2-7 in replication initiation. In The Initiation of DNA Replication in Eukaryotes (2016). Springer. DOI 10.1007/978-3-319-24696-3

Gros J, Kumar C, Lynch G, Yadav T, Whitehouse I & Remus D. Post-licensing Specification of Eukaryotic Replication Origins by Facilitated Mcm2-7 Sliding along DNA. Molecular Cell 2015; 60: 797-807.

Gros J, Devbhandari S & Remus D. Origin plasticity during budding yeast DNA replication in vitro. EMBO J 2014; 33: 621-36.

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