The Jayanta Chaudhuri Lab
Laboratory of Molecular and Cellular Immunology
Recombination, genomic integrity, and heterogeneity in B cells
William T. Yewdell, Youngjun Kim, Priyanka Chowdhury, Colleen M. Lau1, Ryan M. Smolkin, Kalina T. Belcheva, Keith C. Fernandez, Montserrat Cols, Wei-Feng Yen, Bharat Vaidyanathan, Davide Angeletti, Adrian B. McDermott, Jonathan W. Yewdell, Joseph C. Sun, Jayanta Chaudhuri. (2020) A hyper-IgM syndrome mutation in AID disrupts G-quadruplex binding and chromatin localization. Immunity (In Press).
Angeletti, D., I. Kosik, J. J. S. Santos, W. T. Yewdell, C. M. Boudreau, V. V. A. Mallajosyula, M. C. Mankowski, M. Chambers, M. Prabhakaran, H. D. Hickman, A. B. McDermott, G. Alter, J. Chaudhuri, and J. W. Yewdell. (2019) Outflanking immunodominance to target subdominant broadly neutralizing epitopes. Proc Natl Acad Sci USA 116: 13474-13479. PMCID: PMC6986270
Pucella JN, Cols M, Yen W-F, Xu S and Chaudhuri J. The B cell activation induced miR-183 cluster plays a minimal role in canonical primary humoral responses. (2019) J. Immunology; 202(5): 1383-1396. PMCID: PMC6986270
Nicolas L, Cols M, Smolkin R, Fernandez KC, Yewdell WT, Yen W-F, Zha S, Vuong B and Chaudhuri J. ATM influences germinal center integrity.(2019) Cutting Edge: Journal of Immunology; 202 (11): 3137-3142. PMCID: PMC6529280
Yen W-F, Sharma R, Cols M, Lau CM, Chaudhry A, Chowdhury P, Yewdell WT, Vaidyanathan B, Sun A, Coffre M, Pucella JN, Chen C-C, Jasin M, Sun JC, Rudensky AY, Koralob SB and Chaudhuri J. (2019). Distinct requirements of CHD4 during B cell development and antibody response. Cell Reports 27(5):1472-1486. PMCID: PMC6527137
Jayanta Chaudhuri, PhD
- Immunologist Jayanta Chaudhuri studies the mechanisms of immunoglobulin gene diversification.
- PhD, Albert Einstein College of Medicine
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