Developmental Biology Program

The Lorenz Studer Lab

Research

Pictured: Dr. Lorenz Studer
Lorenz Studer, MD
Director, Center for Stem Cell Biology

Our laboratory aims at exploiting recent advances in stem cell biology to develop radically new therapies for degenerative disease and cancer. The main focus in the lab is on the biology and application of human embryonic stem (ES) and human induced pluripotent (iPS) cells. Pluripotent stem cells can provide a truly unlimited source for deriving therapeutically relevant cell types for applications in human disease modeling or regenerative medicine.

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Research Projects

Lorenz Studer Lab

Publications

Baggiolini A, Callahan SJ, Montal E, Weiss JM, Trieu T, Tagore MM, Tischfield SE, Walsh RM, Suresh S, Fan Y, Campbell NR, Perlee SC, Saurat N, Hunter MV, Simon-Vermot T, Huang TH, Ma Y, Hollmann T, Tickoo SK, Taylor BS, Khurana E, Koche RP, Studer L, White RM. Developmental chromatin programs determine oncogenic competence in melanoma. Science. 2021 Sep 3;373(6559):eabc1048. doi: 10.1126/science.abc1048. Epub 2021 Sep 3.PMID: 34516843

Kim TW, Piao J, Koo SY, Kriks S, Chung SY, Betel D, Socci ND, Choi SJ, Zabierowski S, Dubose BN, Hill EJ, Mosharov EV, Irion S, Tomishima MJ, Tabar V, Studer L. Biphasic Activation of WNT Signaling Facilitates the Derivation of Midbrain Dopamine Neurons from hESCs for Translational Use. Cell Stem Cell. 2021 Feb 4;28(2):343-355.e5. doi: 10.1016/j.stem.2021.01.005.PMID: 33545081

Piao J, Zabierowski S, Dubose BN, Hill EJ, Navare M, Claros N, Rosen S, Ramnarine K, Horn C, Fredrickson C, Wong K, Safford B, Kriks S, El Maarouf A, Rutishauser U, Henchcliffe C, Wang Y, Riviere I, Mann S, Bermudez V, Irion S, Studer L, Tomishima M, Tabar V. Preclinical Efficacy and Safety of a Human Embryonic Stem Cell-Derived Midbrain Dopamine Progenitor Product, MSK-DA01. Cell Stem Cell. 2021 Feb 4;28(2):217-229.e7. doi: 10.1016/j.stem.2021.01.004.PMID: 33545080

Guttikonda SR, Sikkema L, Tchieu J, Saurat N, Walsh RM, Harschnitz O, Ciceri G, Sneeboer M, Mazutis L, Setty M, Zumbo P, Betel D, de Witte LD, Pe’er D, Studer L. Fully defined human pluripotent stem cell-derived microglia and tri-culture system model C3 production in Alzheimer’s disease. Nat Neurosci. 2021 Feb 8. doi: 10.1038/s41593-020-00796-z. Online ahead of print.PMID: 33558694

Harschnitz O, Studer L. Human stem cell models to study host-virus interactions in the central nervous system. Nat Rev Immunol. 2021 Jan 4. doi: 10.1038/s41577-020-00474-y. Online ahead of print.PMID: 33398129 Review.

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People

Pictured: Dr. Lorenz Studer

Lorenz Studer, MD

Director, Center for Stem Cell Biology

  • The Studer laboratory investigates human stem cells as tools to understand normal and pathological development in the nervous system and to develop cell-based strategies for regenerative medicine.
  • MD, Universitat Bern
[email protected]
Email Address
212-639-6126
Office Phone

Members

Lorenz Studer
Lorenz Studer

Member

Arianna Baggiolini
Arianna Baggiolini, PhD

Research Fellow

Elizabeth L Calder, PhD
Elizabeth L Calder, PhD

Senior Research Scientist

Gabriele Ciceri, Ph.D.
Gabriele Ciceri, PhD

Senior Research Scientist

Isabelle de Luzy
Isabelle de Luzy, PhD

Research Fellow

Elisa Giacomelli
Elisa Giacomelli, PhD

Research Fellow

James Hackland
James Hackland, PhD

Senior Research Scientist

Oliver Härschnitz
Oliver Härschnitz, MD, PhD

Research Associate - NYSTEM Training Award at the CSCB

Johannes Jungverdorben, PhD
Johannes Jungverdorben, PhD

Research Associate

Noopur Khobrekar
Noopur Khobrekar, PhD

Research Fellow

TaeWan Kim, PhD
TaeWan Kim, PhD

Research Associate

Polina Oberst, PhD
Polina Oberst, PhD

Research Fellow

Nathalie Saurat, PhD
Nathalie Saurat, PhD

Research Associate

Ryan Walsh, PhD
Ryan Walsh, PhD

Research Fellow

Yujie Fan
Yujie Fan

Graduate Student

Emiliano Hergenreder
Emiliano Hergenreder

Graduate Student

So Yeon Koo
So Yeon Koo

Graduate Student

Andrew Minotti
Andrew Minotti

Graduate Student

Samantha Phillips
Samantha Phillips

Graduate Student

Chelsea Rittenhouse
Chelsea Rittenhouse

Graduate Student

Berkiye Sonustun
Berkiye Sonustun

Graduate Student

Nan Xu
Nan Xu

Graduate Student

Jiayi Yuan
Jiayi Yuan

Graduate Student

Angela Pepe-Caprio
Angela Pepe-Caprio

Lab Manager

Alex Henderson
Alex Henderson

Program Manager

Yen Chun "Wenna" Chen
Yen Chun "Wenna" Chen

Lab Technician

Maliha Rahman
Maliha Rahman

Lab Technician

Danaysy Frias
Danaysy Frias

Senior Administrative Assistant

Youjun Wu
Youjun Wu

Senior Research Scientist

Lab Alumni
Eveline Gutzwiller
Eveline Gutzwiller

Postdoctoral Fellow - currently: Neurology resident, Mount Sinai Medical School, New York, NY

Scott J. Callahan
Scott J. Callahan

Vice President, Director of Medical Strategy at Havas Health & You, New York, NY

Gustav Cederquist
Gustav Cederquist

Graduate Student – currently: Resident in Radiation Oncology, Memorial Sloan Kettering Cancer Center

Nadja Zeltner, PhD
Nadja Zeltner

Postdoctoral fellow – currently, Assistant Professor, University of Georgia

Daniela Cornacchia, PhD
Daniela Cornacchia, PhD

Postdoctoral Fellow

Yuchen Qi
Yuchen Qi

Postdoctoral Fellow - currently: Consultant, The Boston Consulting Group

Faranak Fattahi, MS
Faranak Fattahi

Graduate Student - currently, Sandler Faculty Fellow, UCSF

Michelle Vincendeau

Postdoctoral Fellow – currently: Group leader, Helmholtz Zentrum, Munich, Germany

Elsa Vera
Elsa Vera

Postdoctoral Fellow - currently: Senior Machine Learning Engineer - Digital Intelligence at JPMorgan Chase & Co.

Bastian Zimmer, PhD
Bastian Zimmer

Postdoctoral Fellow - currently: Group leader, Evotec, Hamburg, Germany

Mohamed Soliman
Mohamed Soliman

Medical Student, Weill Cornell - currently: Physician/Psychiatrist, Ann Arbor, Michigan

Sarah Kishinevsky
Sarah Kishinevsky

Graduate Student – currently, Director of the Dean's Entrepreneurship Lab at Weill Cornell

Julius Steinbeck

Postdoctoral Fellow - currently: Freelance Neurologist and Stem Cell Expert, Germany

Jason Tchieu
Jason Tchieu

Postdoctoral Fellow - currently: Assistant Professor, Cincinnati Children’s Hospital, Cincinnati, OH

Yosif Martin Ganat
Yosif Martin Ganat

Postdoctoral Fellow - currently: Research Investigator, Arvinas,, New Haven, CT

Sonja Kriks

Postdoctoral Fellow - currently Senior Scientist at Neurona Therapeutics Inc

Sudha Guttikonda
Sudha Guttikonda

Graduate Student

Jae-won Shim

Postdoctoral fellow - currently: Assistant Prof., Soonchunhayng University

Stuart Chambers

Postdoctoral Fellow - currently, Senior Scientist at Amgen

Justine D. Miller

Principal Scientist at AbbVie, Boston, MA

Fabien Lafaille
Fabien Lafaille

PhD student – currently: Senior Scientist, BlueRock Thearpeutics, New York, NY

Yvonne Gruber Mica

Manager, Field Applications - Cell Biology Thermo Fisher Scientific New York, NY

Inna Lipchina

Graduate Student - currently: Senior Scientist, Cellarity

Gabsang Lee

Postdoctoral Fellow - currently: Associate Prof., Johns Hopkins School of Medicine

Sun Young Chung
Sun Young Chung

Lab Technician - currently: medical student, Harvard University

Asif Maroof

Graduate Student - currently: Assistant Professor, The University of Texas at San Antonio

Yechiel Elkabetz

Postdoctoral fellow - Currently: Principal Investigator, Max Planck Institute for Molecular Genetics,

Marietta Saldias Montivero

Lab Technician - currently: MD/PhD student

Sabrina Desbordes

Postdoctoral fellow - currently: Assistant Prof., Helmholtz Institute

Tiziano Barberi
Tiziano Barberi

Postdoctoral Fellow - Currently: Associate Scientist, Texas BioMed Research Institute, SW National Primate Research Center

Mark J Tomishima, PhD
Mark J Tomishima

Currently, Sr. Director, CNS Bioprocess at BlueRock Therapeutics

Viviane Tabar

Chair, Department of Neurosurgery; Theresa Feng Chair in Neurosurgical Oncology

Anselme Perrier
Anselme Perrier

Postdoctoral Fellow - currently: Principal Investigator, iSTEM, INSERM, France

Hyesoo Kim
Hyesoo Kim

Currently, Assistant Professor at Johns Hopkins School of Medicine

Agnete Kirkeby
Agnete Kirkeby

PhD student – currently, Associate Professor of Stem Cell Biology, University of Copenhagen, Denmark

Lab Affiliations

Achievements

  • Jacob & Louise Gabbay Award in Biotechnology & Medicine (2018)
  • Ogawa-Yamanaka Stem Cell Prize, Gladstone Institutes (2017)
  • MacArthur Fellow (2015)
  • Member, American Society of Clinical Investigation (2014)
  • Annemarie Opprecht Parkinson Award, Annemarie Opprecht Foundation (2012)
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  • Louise and Allston Boyer Young Investigator in Basic Research, Memorial Sloan Kettering Cancer Center (2005)

Open Positions

Career Opportunities

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Disclosures

Doctors and faculty members often work with pharmaceutical, device, biotechnology, and life sciences companies, and other organizations outside of MSK, to find safe and effective cancer treatments, to improve patient care, and to educate the health care community.

MSK requires doctors and faculty members to report (“disclose”) the relationships and financial interests they have with external entities. As a commitment to transparency with our community, we make that information available to the public.

Lorenz Studer discloses the following relationships and financial interests:

  • BlueRock Therapeutics
    Intellectual Property Rights; Provision of Services
  • Fujifilm Cellular Dynamics, Inc.
    Intellectual Property Rights
  • Luxa Biotechnology, LLC
    Provision of Services
  • Neurona Therapeutics
    Ownership / Equity Interests; Provision of Services (uncompensated)
  • Rumi Scientific, Inc.
    Provision of Services (uncompensated)
  • Vita Therapeutics, Inc.
    Ownership / Equity Interests; Provision of Services (uncompensated)

The information published here is for a specific annual disclosure period. There may be differences between information on this and other public sites as a result of different reporting periods and/or the various ways relationships and financial interests are categorized by organizations that publish such data.


This page and data include information for a specific MSK annual disclosure period (January 1, 2020 through disclosure submission in spring 2021). This data reflects interests that may or may not still exist. This data is updated annually.

Learn more about MSK’s COI policies here. For questions regarding MSK’s COI-related policies and procedures, email MSK’s Compliance Office at [email protected].


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