Torborg SR, Grbovic-Huezo O, Singhal A, Holm M, Wu K, Han X, Ho Y, Haglund C, Mitchell MJ, Lowe SW, Dow LE, Pitter KL, Sanchez-Rivera FJ, Levchenko A, Tammela T. Solid tumor growth depends on an intricate equilibrium of malignant cell states. bioRxiv [Preprint] 2023.12.30.573100; doi: https://doi.org/10.1101/2023.12.30.573100Li Z, Zhuang X, Pan CH, Yan Y, Thummalapalli R, Hallin J, Torborg SR, Singhal A, Chang JC, Manchado E, Dow LE, Yaeger R, Christensen JG, Lowe S, Rudin CM, Joost S, Tammela T. Alveolar differentiation drives resistance to KRAS inhibition in lung adenocarcinoma. Cancer Discovery, (2024, published online ahead of print 12 Jan).Marjanovic ND, Hofree M, Chan JE, Canner D, Wu K, Trakala M, Hartmann GG, Smith OC, Kim JY, Evans KV, Hudson A, Ashenberg O, Porter CBM, Bejnood A, Subramanian A, Pitter K, Yan Y, Delorey T, Phillips DR, Shah N, Chaudhary O, Tsankov A, Hollmann T, Rekhtman N, Massion PP, Poirier JT, Mazutis L, Li R, Lee JH, Amon A, Rudin CM, Jacks T, Regev A, Tammela T. Emergence of a high-plasticity cell state during lung cancer evolution. Cancer Cell, 38(2):229-246 (2020).Tammela T, Sanchez-Rivera FJ, Malli-Cetinbas N, Joshi NS, Helenius K, Park YK, Azimi R, Wu K, Kerper NR, Wesselhoeft RA, Gu X, Schmidt L, Cornwall-Brady M, Yilmaz ÖH, Xue W, Katajisto P, Bhutkar A, Jacks T. A Wnt-producing niche drives proliferative potential and progression in lung adenocarcinoma. Nature, 545:355-359 (2017). Book traversal links for The Tuomas Tammela Lab Previous Featured News Next Open Positions