Structural Biology Program

The Dinshaw Patel Lab

Research

Pictured: Dinshaw Patel
Dinshaw Patel, PhD

Our group applies crystallographic and solution NMR techniques to investigate macromolecular-mediated recognition, regulation, and catalysis. The major thrust of the laboratory is currently in the structural biology of RNA silencing and epigenetic regulation (histone and DNA methylation marks). Significant efforts are also under way toward a molecular understanding of RNA-mediated events involving riboswitches and ribozymes, as well as protein-RNA recognition events impacting on disease syndromes. A new project addvesses structure-function studies of cytoplasmic metazoan nucleic acid sensors and their cyclic dinucleotide second messengers that activate the innate immune response. Other projects include higher-order DNA architectures and the DNA damage. Finally, our group also studies the molecular basis of glycosphingolipid and phospholipid  binding specificity.

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Research Projects

Dinshaw Patel Lab Group

Publications

People

Pictured: Dinshaw Patel

Dinshaw Patel, PhD

  • The Patel laboratory studies the structural biology of macromolecular recognition, including RNA catalysis, RNA interference, and bypass of DNA damage.
  • PhD, New York University
[email protected]
Email Address
212-639-7207
Office Phone

Members

Pictured: Dinshaw Patel
Dinshaw J. Patel

Member and Laboratory Head

Marianna Teplova
Marianna Teplova

Senior Research Scientist

Malbelyn Fraticelli

Administrator

Ning Jia
Ning Jia

Research Fellow

Vitaly V. Kuryavyi
Vitaly V. Kuryavyi

Senior Research Scientist

Juncheng Wang
Juncheng Wang

Research Fellow

Wei Xie
Wei Xie

Research Fellow

You Yu, PhD
You Yu

Research Fellow

Lab Affiliations

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Disclosures

Doctors and faculty members often work with pharmaceutical, device, biotechnology, and life sciences companies, and other organizations outside of MSK, to find safe and effective cancer treatments, to improve patient care, and to educate the health care community.

MSK requires doctors and faculty members to report (“disclose”) the relationships and financial interests they have with external entities. As a commitment to transparency with our community, we make that information available to the public.

Dinshaw Patel discloses the following relationships and financial interests:

  • Ankrin Therapeutics
    Intellectual Property Rights
  • Chinese Academy of Sciences
    Provision of Services
  • Chinook Therapeutics
    Intellectual Property Rights
  • Harbin Institute of Technology, Harbon, China
    Provision of Services
  • Institute Research Biomedicine, Barcelona, Spain
    Provision of Services
  • Southern University of Science and Technology
    Provision of Services (uncompensated)
  • Takeda Pharmaceuticals
    Intellectual Property Rights
  • Tsinghua University
    Provision of Services (uncompensated)
  • Ventus Therapeutics
    Provision of Services

The information published here is for a specific annual disclosure period. There may be differences between information on this and other public sites as a result of different reporting periods and/or the various ways relationships and financial interests are categorized by organizations that publish such data.


This page and data include information for a specific MSK annual disclosure period (January 1, 2020 through disclosure submission in spring 2021). This data reflects interests that may or may not still exist. This data is updated annually.

Learn more about MSK’s COI policies here. For questions regarding MSK’s COI-related policies and procedures, email MSK’s Compliance Office at [email protected].


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