Developmental Biology Program

The Lorenz Studer Lab

Research

Pictured: Dr. Lorenz Studer
Lorenz Studer, MD
Director, Center for Stem Cell Biology

Our laboratory aims at exploiting recent advances in stem cell biology to develop radically new therapies for degenerative disease and cancer. The main focus in the lab is on the biology and application of human embryonic stem (ES) and human induced pluripotent (iPS) cells. Pluripotent stem cells can provide a truly unlimited source for deriving therapeutically relevant cell types for applications in human disease modeling or regenerative medicine.

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Research Projects

Lorenz Studer Lab

Publications

Kim TW, Piao J, Koo SY, Kriks S, Chung SY, Betel D, Socci ND, Choi SJ, Zabierowski S, Dubose BN, Hill EJ, Mosharov EV, Irion S, Tomishima MJ, Tabar V, Studer L. Biphasic Activation of WNT Signaling Facilitates the Derivation of Midbrain Dopamine Neurons from hESCs for Translational Use. Cell Stem Cell. 2021 Feb 4;28(2):343-355.e5. doi: 10.1016/j.stem.2021.01.005.PMID: 33545081

Piao J, Zabierowski S, Dubose BN, Hill EJ, Navare M, Claros N, Rosen S, Ramnarine K, Horn C, Fredrickson C, Wong K, Safford B, Kriks S, El Maarouf A, Rutishauser U, Henchcliffe C, Wang Y, Riviere I, Mann S, Bermudez V, Irion S, Studer L, Tomishima M, Tabar V. Preclinical Efficacy and Safety of a Human Embryonic Stem Cell-Derived Midbrain Dopamine Progenitor Product, MSK-DA01. Cell Stem Cell. 2021 Feb 4;28(2):217-229.e7. doi: 10.1016/j.stem.2021.01.004.PMID: 33545080

Guttikonda SR, Sikkema L, Tchieu J, Saurat N, Walsh RM, Harschnitz O, Ciceri G, Sneeboer M, Mazutis L, Setty M, Zumbo P, Betel D, de Witte LD, Pe’er D, Studer L. Fully defined human pluripotent stem cell-derived microglia and tri-culture system model C3 production in Alzheimer’s disease. Nat Neurosci. 2021 Feb 8. doi: 10.1038/s41593-020-00796-z. Online ahead of print.PMID: 33558694

Harschnitz O, Studer L. Human stem cell models to study host-virus interactions in the central nervous system. Nat Rev Immunol. 2021 Jan 4. doi: 10.1038/s41577-020-00474-y. Online ahead of print.PMID: 33398129 Review.

Cederquist GY, Tchieu J, Callahan SJ, Ramnarine K, Ryan S, Zhang C, Rittenhouse C, Zeltner N, Chung SY, Zhou T, Chen S, Betel D, White RM, Tomishima M, Studer L. A Multiplex Human Pluripotent Stem Cell Platform Defines Molecular and Functional Subclasses of Autism-Related Genes.. Cell Stem Cell. 2020 Jul 2;27(1):35-49.e6. doi: 10.1016/j.stem.2020.06.004. PMID: 32619517; PMCID: PMC7376579.

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People

Pictured: Dr. Lorenz Studer

Lorenz Studer, MD

Director, Center for Stem Cell Biology

  • The Studer laboratory investigates human stem cells as tools to understand normal and pathological development in the nervous system and to develop cell-based strategies for regenerative medicine.
  • MD, Universitat Bern
[email protected]
Email Address
212-639-6126
Office Phone

Members

Lorenz Studer
Lorenz Studer

Member

Arianna Baggiolini
Arianna Baggiolini, PhD

Research Fellow

Elizabeth L Calder, PhD
Elizabeth L Calder, PhD

Senior Research Scientist

Gabriele Ciceri, Ph.D.
Gabriele Ciceri, PhD

Senior Research Scientist

Isabelle de Luzy, PhD

Research Fellow

Elisa Giacomelli
Elisa Giacomelli, PhD

Research Fellow

James Hackland, PhD
James Hackland, PhD

Senior Research Scientist

Oliver Härschnitz
Oliver Härschnitz, MD, PhD

Research Associate - NYSTEM Training Award at the CSCB

Johannes Jungverdorben, PhD
Johannes Jungverdorben, PhD

Research Associate

Noopur Khobrekar, PhD

Research Fellow

TaeWan Kim, PhD
TaeWan Kim, PhD

Research Associate

Polina Oberst, PhD
Polina Oberst, PhD

Research Fellow

Nathalie Saurat, PhD
Nathalie Saurat, PhD

Research Associate

Ryan Walsh, PhD
Ryan Walsh, PhD

Research Fellow

Yujie Fan
Yujie Fan

Graduate Student

Emiliano Hergenreder
Emiliano Hergenreder

Graduate Student

Chelsea Rittenhouse
Chelsea Rittenhouse

Graduate Student

So Yeon Koo
So Yeon Koo

Graduate Student

Andrew Minotti
Andrew Minotti

Graduate Student

Samantha Phillips
Samantha Phillips

Graduate Student

Jiayi Yuan
Jiayi Yuan

Graduate Student

Nan Xu
Nan Xu

Graduate Student

Angela Pepe-Caprio
Angela Pepe-Caprio

Lab Manager

Maliha Rahman

Lab Technician

Alex Henderson
Alex Henderson

Program Manager

Danaysy Frias
Danaysy Frias

Senior Administrative Assistant

Lab Alumni
Eveline Gutzwiller
Eveline Gutzwiller

Postdoctoral Fellow

Scott J. Callahan, PhD
Scott J. Callahan

Medical Director at Havas Health & You, New York, NY

Gustav Cederquist
Gustav Cederquist

Graduate Student

Nadja Zeltner, PhD
Nadja Zeltner

Postdoctoral fellow – currently, Assistant Professor, University of Georgia

Daniela Cornacchia, PhD
Daniela Cornacchia, PhD

Postdoctoral Fellow

Yuchen Qi
Yuchen Qi

Postdoctoral Fellow - currently: Consultant, The Boston Consulting Group

Faranak Fattahi, MS
Faranak Fattahi

Graduate Student - currently, Sandler Faculty Fellow, UCSF

Michelle Vincendeau

Postdoctoral Fellow – current, Group leader, Helmholtz Zentrum, Munich, Germany

Elsa Vera, PhD
Elsa Vera

Postdoctoral Fellow - currently, Research Associate in The Luis Parada Lab

Bastian Zimmer, PhD
Bastian Zimmer

Postdoctoral Fellow - currently, Head of Stem Cell Protocol Development Core, Evotec, Hamburg, Germany

Mohamed Soliman

Medical Student, Weill Cornell

Sarah Kishinevsky

Graduate Student – currently, Director of the Dean's Entrepreneurship Lab at Weill Cornell

Julius Steinbeck

Postdoctoral Fellow

Jason Tchieu
Jason Tchieu

Postdoctoral Fellow

Yosif Martin Ganat

Postdoctoral Fellow - currently, Staff Scientist at NYSCF

Sonja Kriks

Postdoctoral Fellow - currently Senior Scientist at Neurona Therapeutics Inc

Sudha Guttikonda
Sudha Guttikonda

Graduate Student

Jae-won Shim

Postdoctoral fellow - currently: Assistant Prof., Soonchunhayng University

Stuart Chambers

Postdoctoral Fellow - currently, Senior Scientist at Amgen

Justine D. Miller

Principal Scientist at AbbVie, Boston, MA

Fabien Lafaille

PhD student – currently, Research Associate in the Jean-Laurent Casanova Lab, Rockefeller University

Yvonne Gruber Mica

Manager, Field Applications - Cell Biology Thermo Fisher Scientific New York, NY

Inna Lipchina

Graduate Student - currently: Postdoctoral fellow with Konrad Hochedlinger

Gabsang Lee

Postdoctoral Fellow - currently: Associate Prof., Johns Hopkins School of Medicine

Sun Young Chung
Sun Young Chung

Lab Technician

Asif Maroof

Graduate Student - currently: Assistant Professor, The University of Texas at San Antonio

Yechiel Elkabetz

Postdoctoral fellow - Currently: Principal Investigator, Max Planck Institute for Molecular Genetics,

Marietta Saldias Montivero

Lab Technician

Sabrina Desbordes

Postdoctoral fellow - currently: Assistant Prof., Helmholtz Institute

Tiziano Barberi

Postdoctoral Fellow - Currently: Associate Scientist, Texas BioMed Research Institute, SW National Primate Research Center

Mark J Tomishima, PhD
Mark J Tomishima

Currently, Sr. Director, CNS Bioprocess at BlueRock Therapeutics

Viviane Tabar

Chair, Department of Neurosurgery; Theresa Feng Chair in Neurosurgical Oncology

Anselme Perrier

Postdoctoral Fellow - currently: Principal Investigator, iSTEM, INSERM, France

Hyesoo Kim

Currently, Assistant Professor at Johns Hopkins School of Medicine

Agnete Kirkeby

PhD student – currently, Associate Professor of Stem Cell Biology, University of Copenhagen, Denmark

Lab Affiliations

Achievements

  • Jacob & Louise Gabbay Award in Biotechnology & Medicine (2018)
  • Ogawa-Yamanaka Stem Cell Prize, Gladstone Institutes (2017)
  • MacArthur Fellow (2015)
  • Member, American Society of Clinical Investigation (2014)
  • Annemarie Opprecht Parkinson Award, Annemarie Opprecht Foundation (2012)
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  • Louise and Allston Boyer Young Investigator in Basic Research, Memorial Sloan Kettering Cancer Center (2005)

Open Positions

Career Opportunities

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Disclosures

Doctors and faculty members often work with pharmaceutical, device, biotechnology, and life sciences companies, and other organizations outside of MSK, to find safe and effective cancer treatments, to improve patient care, and to educate the health care community.

MSK requires doctors and faculty members to report (“disclose”) the relationships and financial interests they have with external entities. As a commitment to transparency with our community, we make that information available to the public.

Lorenz Studer discloses the following relationships and financial interests:

  • Bayer
    Ownership / Equity Interests
  • BlueRock Therapeutics
    Intellectual Property Rights; Ownership / Equity Interests; Provision of Services
  • Neurona Therapeutics
    Ownership / Equity Interests; Provision of Services (uncompensated)
  • Vita Therapeutics, Inc.
    Ownership / Equity Interests; Provision of Services (uncompensated)

The information published here is for a specific annual disclosure period. There may be differences between information on this and other public sites as a result of different reporting periods and/or the various ways relationships and financial interests are categorized by organizations that publish such data.


This page and data include information for a specific MSK annual disclosure period (January 1, 2019 through disclosure submission in spring 2020). This data reflects interests that may or may not still exist. This data is updated annually.

Learn more about MSK’s COI policies here. For questions regarding MSK’s COI-related policies and procedures, email MSK’s Compliance Office at [email protected].


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