Sayali Chowdhary, PhD

Postdoctoral Research Scholar

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Sayali Chowdhary

Lab Phone

212-639-8215

Lab Fax

646-422-2355

Education:
2011 – 2019: Integrated PhD (MS + PhD), Indian Institute of Science, Education and Research (IISER), Pune, India (Richa Rikhy lab)

2008 – 2011: B.Sc. in Biotechnology, University of Pune, India

Research Interests:
I am always fascinated by how cells attain different identities and architecture while originating from identical parental cell types and the dynamicity of the tissue behavior as a whole during the process of cell fate determination. In mammalian embryos (blastocysts), the first cell fate determination events occur early during the development, even before implanting into the uterus (pre-implantation).

I am interested in understanding the factors regulating spatiotemporal emergence of the cell identities and positioning in the blastocysts. I employ advanced microscopy and computational tools to document and analyze live-imaged, lineage-specific fluorescent reporters and markers for cell morphology and sorting while the cell fates are established.

Publications

Chowdhary S, Madan S, Tomer D, Mavrakis M, Rikhy R. (2020). Mitochondrial morphology and activity regulate furrow ingression and contractile ring dynamics in Drosophila cellularization. Mol Biol Cell. Oct 1;31(21):2331-2347. doi: 10.1091/mbc.E20-03-0177. Epub 2020 Aug 5. PMID: 32755438; PMCID: PMC7851960.

Chowdhary S, Tomer D, Dubal D, Sambre D, Rikhy R. (2017).  Analysis of mitochondrial organization and function in the Drosophila blastoderm embryo. Sci Rep. Jul 14;7(1):5502. doi: 10.1038/s41598-017-05679-1. PMID: 28710464; PMCID: PMC5511145.