Structural Biology Program
The Richard Hite Lab
Our research group is focused upon determining the mechanisms of intracellular ion transport with a particular focus upon the lysosome. We use a variety of structural and biophysical tools including cryo-electron microscopy, X-ray crystallography and electrophysiology to characterize these channels.
Paknejad N and Hite RK. “Structural basis for the regulation of inositol trisphosphate receptors by Ca2+and IP3.” Nat Struct Mol Biol. 2018. 25:660-668.
Oh S, Paknejad N and Hite RK. “Gating and Selectivity Mechanisms for the Lysosomal K + Channel TMEM175.” eLife. 2020. 9:e53430.
Richard Hite, PhD
- The Hite laboratory studies the mechanisms of intracellular ion transport.
- BS - Emory University
- PhD – Harvard University
- Josie Robertson Investigator (2017-2022)
- Searle Scholar
- Tri-Institutional Breakout Award for Junior Investigators
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Richard Hite discloses the following relationships and financial interests:
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